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Blazein of a new steroid isolated from Agaricus blazei Murrill (himematsutake) induces cell death and morphological change indicative of apoptotic chromatin condensation in human lung cancer LU99 and stomach cancer KATO III cells.

Itoh H, Ito H, Hibasami H.


Oncol Rep. 2008 Dec;20(6):1359-61.

Lack of chemopreventive activity of Agaricus blazei mushroom on the development of 1,2-dimethylhydrazine-induced colonic aberrant crypt foci in rats.

Ribeiro-Santos G, Barbisan LF, Lopes FC, Spinardi-Barbisan AL, da Eira AF, Kaneno R.


Nutr Cancer. 2008;60(6):768-75.

Antioxidative and antimutagenic activities of 70% ethanolic extracts from four fungal mycelia-fermented specialty rices.

Ra Yoon M, Hyun Nam S, Young Kang M.


J Clin Biochem Nutr. 2008 Sep;43(2):118-25.

Black soybean promotes the formation of active components with antihepatoma activity in the fermentation product of Agaricus blazei.

Su ZY, Hwang LS, Kuo YH, Shu CH, Sheen LY.


J Agric Food Chem. 2008 Oct 22;56(20):9447-54.

Tumoricidal effects of beta-glucans: mechanisms include both antioxidant activity plus enhanced systemic and topical immunity.

Gu Y, Fujimiya Y, Itokawa Y, Oshima M, Choi JS, Miura T, Ishida T.


Nutr Cancer. 2008;60(5):685-91.

Lack of chemoprevention of dietary Agaricus blazei against rat colonic aberrant crypt foci.

Ziliotto L, Barbisan LF, Rodrigues MA.


Hum Exp Toxicol. 2008 Jun;27(6):505-11.

Effects of the medicinal mushroom Agaricus blazei Murill on immunity, infection and cancer.

Hetland G, Johnson E, Lyberg T, Bernardshaw S, Tryggestad AM, Grinde B.


Scand J Immunol. 2008 Oct;68(4):363-70.

Nerve growth factor-inducing activity of Hericium erinaceus in 1321N1 human astrocytoma cells.

Mori K, Obara Y, Hirota M, Azumi Y, Kinugasa S, Inatomi S, Nakahata N.


Biol Pharm Bull. 2008 Sep;31(9):1727-32.

Amelioration of skewed Th1/Th2 balance in tumor-bearing and asthma-induced mice by oral administration of Agaricus blazei extracts.

Takimoto H, Kato H, Kaneko M, Kumazawa Y.


Immunopharmacol Immunotoxicol. 2008;30(4):747-60.

Immunomodulating Activity of Agaricus brasiliensis KA21 in Mice and in Human Volunteers.

Liu Y, Fukuwatari Y, Okumura K, Takeda K, Ishibashi KI, Furukawa M, Ohno N, Mori K, Gao M, Motoi M.


Evid Based Complement Alternat Med. 2008 Jun;5(2):205-219.

Agaricus blazei Murill augments keratinocyte production of bioactive cytokines capable of promoting antigen-presenting capacity.

Sugita K, Kabashima K, Tokura Y.


J Dermatol. 2008 Jun;35(6):373-6.

Immunomodulatory capacity of fungal proteins on the cytokine production of human peripheral blood mononuclear cells.

Jeurink PV, Noguera CL, Savelkoul HF, Wichers HJ.


Int Immunopharmacol. 2008 Aug;8(8):1124-33.

The mushroom Agaricus blazei Murill extract normalizes liver function in patients with chronic hepatitis B.

Hsu CH, Hwang KC, Chiang YH, Chou P.


J Altern Complement Med. 2008 Apr;14(3):299-301.

Himematsutake (Iwade Strain 101) extract (ABM-FD): genetic toxicology and a 3-month dietary toxicity study in rats.

Sumiya T, Ikeda Y, Broadmeadow A, May K, Pritchard L, Horne C, Burlinson B.


Food Chem Toxicol. 2008 Jun;46(6):1949-59.

The Medicinal Mushroom Agaricus blazei Murrill: Review of Literature and Pharmaco-Toxicological Problems.

Firenzuoli F, Gori L, Lombardo G.


Evid Based Complement Alternat Med. 2008 Mar;5(1):3-15.

Inhibitory effect of Agaricu blazei Murill components on abnormal collagen fiber formation in human hepatocarcinoma cells.

Sorimachi K, Akimoto K, Koge T.


Biosci Biotechnol Biochem. 2008 Feb;72(2):621-3.

In vitro and in vivo anti-oxidant activity of hot water extract of basidiomycetes-X, newly identified edible fungus.

Watanabe T, Nakajima Y, Konishi T.


Biol Pharm Bull. 2008 Jan;31(1):111-7.

Lack of carcinogenicity of lyophilized Agaricus blazei Murill in a F344 rat two year bioassay.

Lee IP, Kang BH, Roh JK, Kim JR.
ラットによる2年間の発がん性試験 [資料を見る]


Food Chem Toxicol. 2008 Jan;46(1):87-95.